(Idiopathic) Ketotic hypoglycemia in children
نویسنده
چکیده
Idiopathic Ketotic Hypoglycemia is the most common non-iatrogenic cause of hypoglycemia in children beyond infancy. It improves with age and is rare after puberty. Early morning hypoglycemia, responding promptly to glucose, is a typical presentation. Etiology of hypoglycemia is unclear; deficiency of gluconeogenic substrate (hypoalaninemia) has been widely proposed. Idiopathic Ketotic Hypoglycemia is a diagnosis of exclusion. Rule out specific etiologies first. Ketonuria precedes hypoglycemia by several hours, testing for ketonuria helps in early detection. For prevention, avoiding fasting states and bedtime snacks are helpful.
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متن کاملStudies of children with ketotic hypoglycemia.
The work of Ulstrom and his associates,"2 has described many of the features of ketotic hypoglycemia, a syndrome of sporadic hypoglycemia associated with ketosis in children. These investigators have described the following characteristics: hypoglycemia rarely occurred before 18 months of age; it usually occurred after poor dietary intake; acetonuria was present; this kind of hypoglycemia was s...
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Changes in serum free amino acids as a response to ketogenic provocative test were studied in children with a history of ketosis but without hypoglycemia. 1. Of the 17 children who underwent the provocative test, only three showed clinical manifestations. They were among five children who responded to the test and developed hypoglycemia. 2. Hypoglycemic and non-hypoglycemic children differed gr...
متن کاملNormoglycemic Ketonemia as Biochemical Presentation in Ketotic Glycogen Storage Disease.
BACKGROUND According to the textbooks, the ketotic glycogen storage disease (GSD) types 0, III, VI, IX, and XI are associated with fasting ketotic hypoglycemia and considered milder as gluconeogenesis is intact. METHODS A retrospective cohort study of biochemical profiles from supervised clinical fasting studies is performed in ketotic GSD patients in our metabolic center. For data analysis, ...
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